UEF researchers are part of several Finnish Research Flagships and Centres of Excellence. In addition, many have been awarded highly competed ERC grants by the European Research Council.
Finnish Centres of Excellence
The Academy of Finland’s Centre of Excellence Programmes are a success story in Finnish research. Centres of Excellence (CoE) are at the very cutting edge of science in their fields, carving out new avenues for research, developing creative research environments and innovations, and training new talented researchers for the Finnish research and business sectors. The University of Eastern Finland is part of two Centres of Excellence.
Virtual Laboratory for Molecular Level Atmospheric Transformations (2022–2029)
The Centre of Excellence combines atmospheric and computer science to construct a virtual laboratory for atmospheric aerosol formation, interactively integrating experimental and theoretical state-of-the art methods from the fields of chemistry, physics and artificial intelligence. The Centre is led by Professor Hanna Vehkamäki at the University of Helsinki. Professor Kari Lehtinen and Associate Professor Siegfried Schobesberger from the Aerosol Physics Research Group at the University of Eastern Finland are members of the Centre of Excellence.
Aerosol Physics Research Group
The Centre of Excellence of Inverse Modelling and Imaging (2018–2025)
The objective of the Centre of Excellence is to create fundamentally new, efficient, and theoretically sound solutions to practical inverse problems, especially in medical imaging, geophysics and space research, as well as remote sensing and modelling in enviromental and climate research. The director of the Centre is Academy professor Matti Lassas. The University of Eastern Finland is represented by the Computational Physics and Inverse Problems Research Group.
Finnish Flagship Programme
The Academy of Finland’s Flagship Programme is an instrument that supports high-quality research and increases the societal impact emerging from the research. The University of Eastern Finland is part of six Flagships and coordinates three of them.
FAME – Flagship of Advanced Mathematics for Sensing, Imaging and Modelling
(2024–2028)
The FAME Flagship is a multidisciplinary consortium that develops methods of applied mathematics and physics for the benefit of society, including medical imaging, industrial process monitoring, non-destructive structural testing and satellite data analysis. The FAME Flagship is built on cutting-edge research in inverse problems, and it works in close collaboration with industrial and societal partners. The Flagship is led by Professor Tanja Tarvainen at the University of Eastern Finland.
GeneCellNano – The Gene, Cell and Nano Therapy Competence Cluster for the Treatment of Chronic Diseases
(2020–2028)
GeneCellNano Flagship develops new biological drugs, so-called ATMP products, biomarkers and diagnostics for diseases with unmet clinical need. New treatments are developed for cardiovascular diseases and age-related macular degeneration, as well as for brain, ovarian and bladder cancer. The Flagship is led by Professor Seppo Ylä-Herttuala at the University of Eastern Finland.
UNITE – Forest-Human-Machine Interplay - Building Resilience, Redefining Value Networks and Enabling Meaningful Experiences
(2020–2028)
The aim of the UNITE flagship is to diversify forest-related livelihoods, promote the health and well-being effects of forests, safeguard biodiversity and increase the efficiency of forest use management and operations. The Flagship is led by Professor Heli Peltola at the University of Eastern Finland. The Flagship was earlier led by Professor Jyrki Kangas (years 2020-2022).
ACCC – The Atmosphere and Climate Competence Center
(2020–2028)
The ACCC Flagship focuses on research addressing climate change and deteriorating air quality. The mission is to contribute toward achieving carbon neutrality in Finland, EU and global societies, as well contribute to mitigate air pollution to sustain a healthy atmosphere. The Flagship is led by Professor Markku Kulmala at the University of Helsinki. Professor Kari Lehtinen from UEF is the consortium’s deputy director.
iCAN – Digital Precision Cancer Medicine Flagship
(2019–2026)
iCAN flagship is dedicated to improving cancer diagnostics and care by integrating tumour profiling with comprehensive digital health data. The Flagship is led by Professor Satu Mustjoki at the University of Helsinki. Professor Arto Mannermaa is the contact person at the University of Eastern Finland.
PREIN – The Photonics Research and Innovation flagship,
(2019–2026)
PREIN is a Photonics Research and Innovation platform focusing on light-based solutions from scientific excellence to industrial and societal impact. Photonics and light-based technologies play a central role in all areas of modern life, such as telecommunications, energy and environment. The flagship is led by Professor Goëry Genty at the University of Tampere. Professor Jyrki Saarinen from the University of Eastern Finland is the flagship's deputy director.
Research funded by funded by the European Research Council (ERC)
ERC grants are one of Europe’s most respected research funding schemes. Starting Grants are awarded to researchers who are in the early stages of their careers, Consolidator Grants are awarded to those in the middle stages of their careers and Advanced Grants are awarded to well-established researchers. In addition to a high scientific standard, applicants need to display perspectives that reshape our scientific understanding.
Proof of Concept funding is available to those who already have an ERC award to establish proof of concept of an idea that was generated in the course of their ERC-funded projects.
Below are the University of Eastern Finland's ongoing and completed ERC projects.
ERC Advanced Grants
Professor Seppo Ylä-Herttuala, HeartGenes (2021–2026)
The grant was awarded for research addressing severe coronary artery disease and heart failure. The HeartGenes project seeks to develop novel vascular growth factor molecules. These molecules enable what is known as biological bypass, which seeks to improve circulation in an ischemic heart and to enhance its metabolism and energy supply. The project uses advanced catheter methods by which gene delivery to the heart muscle is performed locally both from the inner lining of heart ventricles and through retrograde delivery, i.e., by cleverly using of the heart’s own venous system as a delivery route.
Earlier ERC Advanced Grant projects:
- Professori Helmi Järviluoma-Mäkelä: Sensory Transformations and Transgenerational Environmental Relationships in Europe, 1950–2020 (SENSOTRA), 2016–2021
- Professor Seppo Ylä-Herttuala: Novel Gene Therapy Based on the Activation of Endogenous Genes for the Treatment of Ischemia - Concepts of endogenetherapy, release of promoter pausing, promoter-targeted ncRNAs and nuclear RNAi (CleverGenes), 2015–2021
- Professor Seppo Ylä-Herttuala: Gene Transfer Techniques in the Treatment of Cardiovascular Diseases and Malignant Glioma (FutureGenes), 2010–2015
ERC Consolidator Grants
Professor Minna Kaikkonen-Määttä, SECRET (2024–2028)
The SECRET project aims for more accurate prediction of the risks associated with atherosclerotic cardiovascular diseases, such as stroke and heart attack. Current health care risk assessment tools do not account for genetic risk factors, which can significantly contribute to an individual's overall risk. The research team aims to revolutionise risk assessment using advanced methods based on single-cell sequencing and CRISPR technology. The team's goal is to develop next-generation tools for determining a patient's individual polygenic risk score. These tools will consider the effects of various genetic factors, including those regulating gene function at the cellular level. The project will produce the largest single cell sequencing dataset of human atherosclerotic plaques to date. Furthermore, the project will explore the function of genes involved in disease development within the vascular wall with unprecedented precision.
Professor Tarja Malm, HUMANE (2022–2027)
Neuroinflammatory reactions geared by malfunctional microglia play a role in the development of Alzheimer’s disease (AD). The HUMANE project combines state-of-the-art techniques to answer how and which glial cell subpopulations are associated with altered neuronal network activities at subcellular and spatial resolution in the human brain in early AD. These events also contribute to a detectable vesicle-based biomarker profile in cerebrospinal fluid and blood prior to the clinical disease. The researchers will utilise brain biopsies obtained from normal pressure hydrocephalus (iNPH) patients. As some of these patients manifest early AD pathology, their brains offer a unique window to evaluate cellular and molecular events occurring during early AD. The project will provide a holistic view on early AD pathology and pinpoint novel molecular targets for further validation and new fluid biomarkers.
Professor Tanja Tarvainen, QUANTOM (2021–2026)
The QUANTOM project delelops novel quantitative imaging modalities based on coupled physics. Coupled physics imaging combines the benefits of two physical phenomena, such as light and ultrasound through the photoacoustic effect. The research aims at the development of quantitative tomographic techniques utilising methods of Bayesian inverse problems. The aim is to provide new imaging modalities for biomedical imaging and research.
ERC Starting Grants
Associate Professor Kaisa Huhta, INTEL (2024–2029)
The INTEL project focuses on developing the general doctrine of energy law. The project will identify and analyse the concepts and principles of energy law, developing the general doctrine for the discipline. A general doctrine consolidates the foundations of a legal discipline and guides legislators, courts and lawyers in identifying, valuing and interpreting legal norms.
The project will combine jurisprudence, interviews, co-creation and machine learning to generate new knowledge on the interpretation of sources of energy law, and on how legislators, judges and lawyers perceive energy law.
Associate Professor Miina Porkka, AQUAGUARD (2024–2028)
Freshwater plays a central role in regulating many life-supporting processes on Earth. Human actions, such as global warming, irrigation, land use and water infrastructure, threaten these processes by modifying the water cycle at an unprecedented rate and scale. The AQUAGUARD project aims to quantify human-driven water cycle changes and their impacts. The goal is to identify ways to safeguard freshwater’s life-supporting functions in the future. The researchers will integrate knowledge and data from various fields of study and use data analysis and modeling techniques to generate new insights that enable a better consideration of the global perspective in water management and governance.
Senior researcher Samuli Junttila, DRYTREE (2024-2028)
The research project aims to revolutionise our understanding of how environmental factors drive tree mortality across species and forest biomes. His research will use cutting-edge remote sensing technology and deep learning methods to quantify spatial and temporal tree mortality patterns, covering hundreds of millions of trees across large regions in Europe and the US. The data gathered will be unprecedented in detail, capturing the 3D structure of individual trees as well as their specific environmental conditions.
Completed ERC Starting Grant projects:
- Associate Professor Alina Solomon, Brain Health Toolbox (2019–2024)
- Professor Minna Kaikkonen-Määttä, Enhancers Decoding the Mechanisms Underlying CAD Risk (EnDeCAD), 2019–2023
- Professor Kati Kulovesi: Slowing Down Climate Change: Combining Climate Law and Climate Science to Identify the Best Options to Reduce Emissions of Short-lived Climate Forcers in Developing Countries (CLIMASLOW), 2017–2022
- Professor Annele Virtanen: Quantifying the atmospheric implications of the solid phase and phase transitions of secondary organic aerosols (QAPPA), 2014–2019
- Professor Rami Korhonen: Evaluation of Osteoarthritis Progression in a Patient-Spesific Manner using Magnetic Resonance Imaging and Computational Modeling (OAPROGRESS), 2011–2016
Completed ERC Proof of Concept projects:
- Professor Rami Korhonen, Novel algorithm for treatment planning of patients with osteoarthritis (ALGOA), 2018-2019