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Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.
There are currently no approved medications for amphetamine addiction. In a large register-based study, the ADHD medication lisdexamfetamine was associated with the best outcomes.
PBPK modeling is extensively used during drug development.